DAVID A. WHEELER, Ph.D., GENETICS
Dr. David A. Wheeler is an associate professor in Baylor College of Medicine's Human Genome Sequencing Center (HGSC). He joined the HBSC in 2001, where he guided the finishing of the D. melanogaster chromosome 3 and X genome sequence in 2002, followed by the human genome sequence, chromosomes 3, and 12, in 2003.Currently, Dr. Wheeler is director of cancer genomics and assistant director of the HGSC. He leads the development of methods for discovery of genome variation in human and animal populations using DNA sequencing technologies with the goal of relating polymorphism to human disease.
Wheeler received his bachelor of science degrees in biochemistry and zoology from the University of Maryland and a master of science in biochemistry from the George Washington University. He earned his Ph.D. in genetics from the George Washington University, and conducted postdoctoral research in behavioral genetics at Brandeis University.
He successfully transferred the courtship song rhythm of D. simulans to D. melanogaster by creating transgenic melanogaster carrying the simulans gene. Through this effort, he became interested in the new field of bioinformatics. He joined the laboratory of Charles Lawrence in 1991 at Baylor College of Medicine, in order to develop computational tools for moloecular biology. He also directed the Molecular Biology Computation Resource at Baylor College of Medicine for 10 years before joining the HGSC.
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